A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies
Jing Xu, Xiaolu Zhao, Fengbiao Mao, Venkatesha Basrur, Beatrix Ueberheide, Brian T Chait, C David Allis, Sean D Taverna, Shan Gao, Wei Wang, and Yifan Liu
Nucleic Acids Research, gkaa1262, https://doi.org/10.1093/nar/gkaa1262
A pan-cancer atlas of somatic mutations in miRNA biogenesis genes
Paulina Galka-Marciniak, Martyna Olga Urbanek-Trzeciak, Paulina Maria Nawrocka, and Piotr Kozlowski
Nucleic Acids Research, Volume 49, Issue 2, 25 January 2021, Pages 601–620, https://doi.org/10.1093/nar/gkaa1223
Regulation of ex-translational activities is the primary function of the multi-tRNA synthetase complex
Haissi Cui, Mridu Kapur, Jolene K Diedrich, John R Yates III, Susan L Ackerman, and Paul Schimmel
Nucleic Acids Research, gkaa1183, https://doi.org/10.1093/nar/gkaa1183
High-resolution visualization and quantification of nucleic acid–based therapeutics in cells and tissues using Nanoscale secondary ion mass spectrometry (NanoSIMS)
Cuiwen He, Michael T Migawa, Kai Chen, Thomas A Weston, Michael Tanowitz, Wenxin Song, Paul Guagliardo, K Swaminathan Iyer, C Frank Bennett, Loren G Fong, Punit P Seth, Stephen G Young, and Haibo Jiang
Nucleic Acids Research, Volume 49, Issue 1, 11 January 2021, Pages 1–14, https://doi.org/10.1093/nar/gkaa1112
Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy
Anna Wacker, Julia E Weigand, Sabine R Akabayov, …, Maria A Wirtz Martin, Jens Wöhnert, and Heidi Zetzsche
Nucleic Acids Research, Volume 48, Issue 22, 16 December 2020, Pages 12415–12435, https://doi.org/10.1093/nar/gkaa1013
Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements
Ilaria Manfredonia, Chandran Nithin, Almudena Ponce-Salvatierra, Pritha Ghosh, Tomasz K Wirecki, Tycho Marinus, Natacha S Ogando, Eric J Snijder, Martijn J van Hemert, Janusz M Bujnicki, and Danny Incarnato
Nucleic Acids Research, gkaa1183, https://doi.org/10.1093/nar/gkaa1183
Construction of a highly error-prone DNA polymerase for developing organelle mutation systems
Junwei Ji, and Anil Day
Nucleic Acids Research, Volume 48, Issue 21, 2 December 2020, Pages 11868–11879, https://doi.org/10.1093/nar/gkaa929
Contribution of DNA adenine methylation to gene expression heterogeneity in Salmonella enterica
María A Sánchez-Romero, David R Olivenza, Gabriel Gutiérrez, and Josep Casadesús
Nucleic Acids Research, Volume 48, Issue 21, 2 December 2020, Pages 11857–11867, https://doi.org/10.1093/nar/gkaa730
Rational design of minimal synthetic promoters for plants
Yao-Min Cai, Kalyani Kallam, Henry Tidd, Giovanni Gendarini, Amanda Salzman, and Nicola J Patron
Nucleic Acids Research, Volume 48, Issue 21, 2 December 2020, Pages 11845–11856, https://doi.org/10.1093/nar/gkaa682
Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates
Christopher R Brown, Swati Gupta, June Qin, Timothy Racie, Guo He, Scott Lentini, Ryan Malone, Mikyung Yu, Shigeo Matsuda, Svetlana Shulga-Morskaya, Anil V Nair, Christopher S Theile, Karyn Schmidt, Azar Shahraz, Varun Goel, Rubina G Parmar, Ivan Zlatev, Mark K Schlegel, Jayaprakash K Nair, Muthusamy Jayaraman, Muthiah Manoharan, Dennis Brown, Martin A Maier, and Vasant Jadhav
Nucleic Acids Research, Volume 48, Issue 21, 2 December 2020, Pages 11827–11844, https://doi.org/10.1093/nar/gkaa670
Pentatricopeptide repeats of protein-only RNase P use a distinct mode to recognize conserved bases and structural elements of pre-tRNA
Takamasa Teramoto, Kipchumba J Kaitany, Yoshimitsu Kakuta, Makoto Kimura, Carol A Fierke, and Traci M Tanaka Hall
Nucleic Acids Research, Volume 48, Issue 21, 2 December 2020, Pages 11815–11826, https://doi.org/10.1093/nar/gkaa627
Alignment and quantification of ChIP-exo crosslinking patterns reveal the spatial organization of protein–DNA complexes
Naomi Yamada, Matthew J Rossi, Nina Farrell, B Franklin Pugh, Shaun Mahony
Nucleic Acids Research, Volume 48, Issue 20, 18 November 2020, Pages 11215–11226, https://doi.org/10.1093/nar/gkaa618
Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints
Eric Vallabh Minikel, Hien T Zhao, Jason Le, Jill O’Moore, Rose Pitstick, Samantha Graffam, George A Carlson, Michael P Kavanaugh, Jasna Kriz, Jae Beom Kim Jiyan Ma, Holger Wille, Judd Aiken, Deborah McKenzie, Katsumi Doh-ura, Matthew Beck, Rhonda O’Keefe, Jacquelyn Stathopoulos, Tyler Caron, Stuart L Schreiber, Jeffrey B Carroll, Holly B Kordasiewicz, Deborah E Cabin, and Sonia M Vallabh
Nucleic Acids Research, Volume 48, Issue 19, 4 November 2020, Pages 10615–10631, https://doi.org/10.1093/nar/gkaa616
PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response
Lisa Aberle, Annika Krüger, Julia M Reber, Michelle Lippmann, Matthias Hufnagel, Michael Schmalz, Irmela R E. A. Trussina, Sarah Schlesiger, Tabea Zubel, Karina Schütz, Andreas Marx, Andrea Hartwig, Elisa Ferrando-May, Alexander Bürkle, and Aswin Mangerich
Nucleic Acids Research, Volume 48, Issue 18, 09 October 2020, Pages 10015–10033, https://doi.org/10.1093/nar/gkaa590
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding
Aleksandra Skrajna, Dennis Goldfarb, Katarzyna M Kedziora, Emily M Cousins, Gavin D Grant, Cathy J Spangler, Emily H Barbour, Xiaokang Yan, Nathaniel A Hathaway, Nicholas G Brown, Jeanette G Cook, Michael B Major, and Robert K McGinty
Nucleic Acids Research, Volume 48, Issue 17, 25 September 2020, Pages 9415–9432, https://doi.org/10.1093/nar/gkaa544
IncC conjugative plasmids and SXT/R391 elements repair double-strand breaks caused by CRISPR–Cas during conjugation
David Roy, Kevin T Huguet, Frédéric Grenier, and Vincent Burrus
Nucleic Acids Research, Volume 48, Issue 16, 18 September 2020, Pages 8815–8827, https://doi.org/10.1093/nar/gkaa518
5′-fluoro(di)phosphate-labeled oligonucleotides are versatile molecular probes for studying nucleic acid secondary structure and interactions by 19F NMR
Marek R Baranowski, Marcin Warminski, Jacek Jemielity, and Joanna Kowalska
Nucleic Acids Research, Volume 48, Issue 15, 04 September 2020, Pages 8209–8224, https://doi.org/10.1093/nar/gkaa470
Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage
Cassandra K Hayne, Casey A Schmidt, Maira I Haque, A Gregory Matera, and Robin E Stanley
Nucleic Acids Research, Volume 48, Issue 14, 20 August 2020, Pages 7609–7622, https://doi.org/10.1093/nar/gkaa438
Synthetic promoter design in Escherichia coli based on a deep generative network
Ye Wang, Haochen Wang, Lei Wei, Shuailin Li, Liyang Liu, and Xiaowo Wang
Nucleic Acids Research, Volume 48, Issue 12, 09 July 2020, Pages 6403–6412, https://doi.org/10.1093/nar/gkaa325
Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks
Noah P Bradley, Lauren A Washburn, Plamen P Christov, Coran M H Watanabe, and Brandt F Eichman
Nucleic Acids Research, Volume 48, Issue 13, 27 July 2020, Pages 7005–7017, https://doi.org/10.1093/nar/gkaa346
Prp5−Spt8/Spt3 interaction mediates a reciprocal coupling between splicing and transcription
Wei Shao, Zhan Ding, Zeng-Zhang Zheng, Ji-Jia Shen, Yu-Xian Shen, Jia Pu, Yu-Jie Fan, Charles C Query, and Yong-Zhen Xu
Nucleic Acids Research, Volume 48, Issue 11, 19 June 2020, Pages 5799–5813, https://doi.org/10.1093/nar/gkaa311
Ribosome profiling in archaea reveals leaderless translation, novel translational initiation sites, and ribosome pausing at single codon resolution
Diego Rivera Gelsinger, Emma Dallon, Rahul Reddy, Fuad Mohammad, Allen R Buskirk, and Jocelyne DiRuggiero
Nucleic Acids Research, Volume 48, Issue 10, 04 June 2020, Pages 5201–5216, https://doi.org/10.1093/nar/gkaa304
H2A.Z is dispensable for both basal and activated transcription in post-mitotic mouse muscles
Edwige Belotti, Nicolas Lacoste, Thomas Simonet, Christophe Papin, Kiran Padmanabhan, Isabella Scionti, Yann-Gaël Gangloff, Lorrie Ramos, Defne Dalkara, Ali Hamiche, Stefan Dimitrov, and Laurent Schaeffer
Nucleic Acids Research, Volume 48, Issue 13, 27 July 2020, Pages 7005–7017, https://doi.org/10.1093/nar/gkaa346
Spatially regulated editing of genetic information within a neuron
Isabel C Vallecillo-Viejo, Noa Liscovitch-Brauer, Juan F Diaz Quiroz, Maria F Montiel-Gonzalez, Sonya E Nemes, Kavita J Rangan, Simon R Levinson, Eli Eisenberg, and Joshua J C Rosenthal
Nucleic Acids Research, Volume 48, Issue 8, 07 May 2020, Pages 3999–4012, https://doi.org/10.1093/nar/gkaa172
Biphasic unbinding of a metalloregulator from DNA for transcription (de)repression in Live Bacteria
Won Jung, Kushal Sengupta, Brian M Wendel, John D Helmann, and Peng Chen
Nucleic Acids Research, Volume 48, Issue 5, 18 March 2020, Pages 2199–2208, https://doi.org/10.1093/nar/gkaa056
The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5′ cap modulates protein expression in living cells
Pawel J. Sikorski, Marcin Warminski, Dorota Kubacka, Tomasz Ratajczak, Dominika Nowis, Joanna Kowalska, and Jacek Jemielity
Nucleic Acids Research, Volume 48, Issue 4, 28 February 2020, Pages 1607–1626, https://doi.org/10.1093/nar/gkaa032
Structural basis of non-canonical transcriptional regulation by the σA-bound iron-sulfur protein WhiB1 in M. tuberculosis
Tao Wan, Shanren Li, Daisy Guiza Beltran, Andrew Schacht, Lu Zhang, Donald F Becker, and LiMei Zhang
Nucleic Acids Research, Volume 48, Issue 2, 24 January 2020, Pages 501–516, https://doi.org/10.1093/nar/gkz1133
Alliance of Genome Resources Portal: unified model organism research platform
The Alliance of Genome Resources Consortium
Nucleic Acids Research, Volume 48, Issue D1, 08 January 2020, Pages D650–D658, https://doi.org/10.1093/nar/gkz813
The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures
Antonina Andreeva, Eugene Kulesha, Julian Gough, and Alexey G Murzin
Nucleic Acids Research, Volume 48, Issue D1, 08 January 2020, Pages D376–D382, https://doi.org/10.1093/nar/gkz1064