2015 Breakthrough Articles

Biogenesis and growth phase-dependent alteration of 5-methoxycarbonylmethoxyuridine in tRNA anticodons

Yusuke Sakai, Kenjyo Miyauchi, Satoshi Kimura and Tsutomu Suzuki

Nucl. Acids Res. (29 January 2016) 44 (2): 509-523. doi: 10.1093/nar/gkv1470

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Automated physics-based design of synthetic riboswitches from diverse RNA aptamers

Amin Espah Borujeni, Dennis M. Mishler, Jingzhi Wang, Walker Huso and Howard M. Salis

Nucl. Acids Res. (08 January 2016) 44 (1): 1-13. doi: 10.1093/nar/gkv1289

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The casposon-encoded Cas1 protein from Aciduliprofundum boonei is a DNA integrase that generates target site duplications

Alison B. Hickman and Fred Dyda

Nucl. Acids Res. (15 December 2015) 43 (22): 10576-10587. doi: 10.1093/nar/gkv1180

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dbMAE: the database of autosomal monoallelic expression

Virginia Savova, Jon Patsenker, Sébastien Vigneau and Alexander A. Gimelbrant

Nucl. Acids Res. 44 (D1): D753-D756. doi: 10.1093/nar/gkv1106

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DIDA: A curated and annotated digenic diseases database

Andrea M. Gazzo, Dorien Daneels, Elisa Cilia, Maryse Bonduelle, Marc Abramowicz, Sonia Van Dooren, Guillaume Smits and Tom Lenaerts

Nucl. Acids Res. 44 (D1): D900-D907. doi: 10.1093/nar/gkv1068

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Methylation of histone H3 lysine 9 occurs during translation

Carlos Rivera, Francisco Saavedra, Francisca Alvarez, César Díaz-Celis, Valentina Ugalde, Jianhua Li, Ignasi Forné, Zachary A. Gurard-Levin, Geneviève Almouzni, Axel Imhof and Alejandra Loyola

Nucl. Acids Res. (30 October 2015) 43 (19): 9097-9106. doi: 10.1093/nar/gkv929

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Structure of a human translation termination complex

Sarah Matheis, Otto Berninghausen, Thomas Becker and Roland Beckmann

Nucl. Acids Res. (15 October 2015) 43 (18): 8615-8626. doi: 10.1093/nar/gkv909

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FDF-PAGE: a powerful technique revealing previously undetected small RNAs sequestered by complementary transcripts

C. Jake Harris, Attila Molnar, Sebastian Y. Müller and David C. Baulcombe

Nucl. Acids Res. (3 September 2015) 43 (15): 7590-7599. doi: 10.1093/nar/gkv604

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Telomere-associated proteins add deoxynucleotides to terminal proteins during replication of the telomeres of linear chromosomes and plasmids in Streptomyces

Chien-Chin Yang, Shu-Min Tseng1 and Carton W. Chen

Nucl. Acids Res. (27 July 2015) 43 (13): 6373-6383. doi: 10.1093/nar/gkv302

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A new transcription factor for mitosis: in Schizosaccharomyces pombe, the RFX transcription factor Sak1 works with forkhead factors to regulate mitotic expression

Angad Garg Bruce Futcher and Janet Leatherwood

Nucl. Acids Res. (18 August 2015) 43 (14): 6874-6888. doi: 10.1093/nar/gkv274

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Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies

Siu Chiu Chan, Luke A. Selth, Yingming Li, Michael D. Nyquist, Lu Miao, James E. Bradner, Ganesh V. Raj, Wayne D. Tilley and Scott M. Deh

Nucl. Acids Res. (13 July 2015) 43 (12): 5880-5897. doi: 10.1093/nar/gkv262

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Next-generation sequencing reveals the biological significance of the N2,3-ethenoguanine lesion in vivo

Shiou-chi Chang, Bogdan I. Fedeles, Jie Wu, James C. Delaney, Deyu Li, Linlin Zhao, Plamen P. Christov, Emily Yau, Vipender Singh, Marco Jost, Catherine L. Drennan, Lawrence J. Marnett, Carmelo J. Rizzo, Stuart S. Levine, F. Peter Guengerich and John M. Essigmann

Nucl. Acids Res. (23 June 2015) 43 (11): 5489-5500. doi: 10.1093/nar/gkv243

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H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes

Mariona Nadal-Ribelles, Glòria Mas, Gonzalo Millán-Zambrano, Carme Solé, Gustav Ammerer, Sebastián Chávez, Francesc Posas and Eulàlia de Nadal

Nucl. Acids Res. (26 May 2015) 43 (10): 4937-4949. doi: 10.1093/nar/gkv220

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Integrating motif, DNA accessibility and gene expression data to build regulatory maps in an organism

Charles Blatti, Majid Kazemian, Scot Wolfe, Michael Brodsky and Saurabh Sinha

Nucl. Acids Res. (30 April 2015) 43 (8): 3998-4012. doi: 10.1093/nar/gkv195

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AKT phosphorylates H3-threonine 45 to facilitate termination of gene transcription in response to DNA damage

Jong-Hyuk Lee, Byung-Hee Kang, Hyonchol Jang, Tae Wan Kim, Jinmi Choi, Sojung Kwak, Jungwon Han, Eun-Jung Cho and Hong-Duk Youn

Nucl. Acids Res. (19 May 2015) 43 (9): 4505-4516. doi: 10.1093/nar/gkv176

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Crystal structure of Hop2–Mnd1 and mechanistic insights into its role in meiotic recombination

Hyun-Ah Kang, Ho-Chul Shin, Alexandra-Styliani Kalantzi, Christopher P. Toseland, Hyun-Min Kim, Stephan Gruber, Matteo Dal Peraro and Byung-Ha Oh

Nucl. Acids Res. (20 April 2015) 43 (7): 3841-3856. doi: 10.1093/nar/gkv172

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CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

Jayan Rammohan, Ana Ruiz Manzano, Ashley L. Garner, Christina L. Stallings and Eric A. Galburt

Nucl. Acids Res. (31 March 2015) 43 (6): 3272-3285. doi: 10.1093/nar/gkv078

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Sequence-specific cleavage of dsRNA by Mini-III RNase

Dawid Głów, Dariusz Pianka, Agata A. Sulej, Łukasz P. Kozłowski, Justyna Czarnecka, Grzegorz Chojnowski, Krzysztof J. Skowronek and Janusz M. Bujnicki

Nucl. Acids Res. (11 March 2015) 43 (5): 2864-2873. doi: 10.1093/nar/gkv009

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